Concepedia

Transduction Efficiency Optimization

Transduction Efficiency Optimization is a methodological framework in ex vivo gene therapy research designed to enhance the proportion of target cells successfully genetically modified by viral vectors through systematic refinement of transduction parameters.

233

Publications

10.5K

Citations

1.4K

Authors

454

Institutions

Publications per year

2017–2026

61

Parents

Publications

233

Adeno-Associated Virus Type 6 (AAV6) Vectors Mediate Efficient Transduction of Airway Epithelial Cells in Mouse Lungs Compared to That of AAV2 Vectors

Christine L. Halbert, James M. Allen, A. Dusty Miller · Journal of Virology · 2001 · 313 citations · Full text

, , +16

High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency

Eduard Ayuso, Federico Mingozzi, Joel Montané et al. · Gene Therapy · 2009 · 278 citations

, , +13

Preclinical Development of Bivalent Chimeric Antigen Receptors Targeting Both CD19 and CD22

Haiying Qin, Sneha Ramakrishna, Sang M. Nguyen et al. · Molecular Therapy — Oncolytics · 2018 · 277 citations · Full text

, , +17

A brain microvasculature endothelial cell‐specific viral vector with the potential to treat neurovascular and neurological diseases

Jakob Körbelin, Godwin Dogbevia, Stefan Michelfelder et al. · EMBO Molecular Medicine · 2016 · 264 citations · Full text

, , +16

High-efficiency retroviral-mediated gene transfer into human and nonhuman primate peripheral blood lymphocytes.

Bruce A. Bunnell, Linda Muul, Robert E. Donahue et al. · Proceedings of the National Academy of Sciences · 1995 · 261 citations

, , +12

1–5 of 233

Authors

1.4K

  1. AS
    Arun Srivastava

    University of Florida, United States

    16 publications · 762 citations

    14

    h-index

  2. CL
    Chen Ling

    University of Florida, United States

    10 publications · 415 citations

    10

    h-index

  3. GR
    Giridhara R. Jayandharan

    Christian Medical College, Vellore, India

    8 publications · 415 citations

    8

    h-index

  4. HM
    Hiroyuki Mizuguchi

    The University of Osaka, Japan

    7 publications · 172 citations

    7

    h-index

  5. MA
    Mavis Agbandje‐McKenna

    University of Florida, United States

    6 publications · 486 citations

    6

    h-index

1–5 of 1.4K

Institutions

454

  1. University of Florida

    Gainesville, United States

    17 h-index

    120 publications

    6.8K citations

  2. Florida College

    Temple Terrace, United States

    14 h-index

    112 publications

    5.8K citations

  3. University of Florida Health

    Gainesville, United States

    10 h-index

    15 publications

    550 citations

  4. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    9 h-index

    31 publications

    2.7K citations

  5. National Institutes of Health

    Bethesda, United States

    8 h-index

    45 publications

    3.6K citations

  6. Central South University

    Changsha, China

    6 h-index

    12 publications

    633 citations

  7. Stanford University

    Stanford, United States

    6 h-index

    22 publications

    639 citations

  8. Chinese Academy of Sciences

    Beijing, China

    6 h-index

    24 publications

    667 citations

1–8 of 454

Venues

  1. Human Gene Therapy

    21 publications · 990 citations

    17

    h-index

  2. Gene Therapy

    15 publications · 873 citations

    14

    h-index

  3. The Journal of Gene Medicine

    15 publications · 431 citations

    13

    h-index

  4. Molecular Therapy

    11 publications · 672 citations

    11

    h-index

  5. 8

    h-index

1–5