Concepedia

Publication | Open Access

Innate Immune Receptor Genetic Polymorphisms in Pouchitis: Is CARD15 a Susceptibility Factor?

DOIFull Paper Access

89

Citations

70

References

2005

Year

Carmen B. Meier, Refaat Hegazi, James Aisenberg, Peter Legnani, Naris Nilubol, Gena M. Cobrin, Richard H. Duerr, Stephen R. Gorfine, Joel J. Bauer, David B. Sachar,
Inflammatory Bowel Diseases

Abstract

CARD15 polymorphisms are seen in greater frequency in patients with pouchitis after IPAA for UC. These findings, if borne out in prospective analyses, suggest that CARD15 mutations, particularly L1007fsinsC, may predispose to the development of pouchitis after IPAA for UC.

References

YearCitations

Page 1