Isotope effects on enzyme-catalyzed reactions

Hydrogen Tunneling in Enzyme Reactions

Yuan Cha, Christopher J L Murray, Judith P. Klinman · Science · 1989 · 480 citations

Natural Sciences, Biochemistry, Chemistry +17

[29] Solvent isotope effects on enzyme systems

K. Barbara Schowen, Richard L. Schowen · Methods in enzymology on CD-ROM/Methods in enzymology · 1982 · 406 citations

Life Sciences, Biochemistry, Chemistry +12

Human immunodeficiency virus-1 protease. 2. Use of pH rate studies and solvent kinetic isotope effects to elucidate details of chemical mechanism

Lawrence J. Hyland, Thaddeus A. Tomaszek, Thomas D. Meek · Biochemistry · 1991 · 245 citations

Life Sciences, Biochemistry, Molecular Biology +13

Simulations of quantum mechanical corrections for rate constants of hydride-transfer reactions in enzymes and solutions

J.-K. Hwang, Z. T. Chu, Anil Yadav et al. · The Journal of Physical Chemistry · 1991 · 203 citations

Natural Sciences, Biochemistry, Chemistry +17

Mechanistic studies of peptidyl prolyl cis-trans isomerase: evidence for catalysis by distortion

Richard K. Harrison, Ross L. Stein · Biochemistry · 1990 · 165 citations

Life Sciences, Biochemistry, Pharmacology +17