Reciprocal control of inflammatory cytokines, IL-1 and IL-6, and β-amyloid production in cultures

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Nucleic Acid Chemistry, Engineering, Natural Sciences +7

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Engineering, Natural Sciences, Rna Isolation +7

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Alison Goate, Marie‐Christine Chartier‐Harlin, Jeremy Brown et al. · Nature · 1991 · 4.6K citations

Alzheimer's Disease, Genetics, Missense Mutation +9

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

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Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease.

W. Sue T. Griffin, Laura Stanley, Lon R. White et al. · Proceedings of the National Academy of Sciences · 1989 · 1.8K citations · Full text

Immunology, Neurochemical Biomarkers, Glioma +22