Annals of Nutrition and Metabolism · 1987 · 33 citations · 11 references
Public HealthNutritionNutritional SciencesHuman NutritionMicronutrient DeficiencyNutritional EpidemiologyCardiovascular DiseaseCardiovascular EpidemiologyIschemic Heart DiseaseZinc MetabolismLinear Discriminant AnalysisSerum Zinc BiomarkersStatistical Discriminant Analysis
Increased Zn/Cu ratio in the diet, and consequently in the body, was suggested to be of importance in the pathogenesis of atherosclerosis. Head hair of 29 male survivors of myocardial infarction and of 23 control males was studied for the concentration of Zn and Cu. The Zn hair concentration and Zn/Cu ratio in survivors of myocardial infarction was significantly higher in comparison with controls. The inclusion of the Zn/Cu ratio into the discriminant analysis using total cholesterol and HDL cholesterol considerably improved the coefficient R2 and decreased the number of cases not properly classified.
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Coronary heart disease: the zinc/copper hypothesis
LM Klevay · American Journal of Clinical Nutrition · 1975 · 259 citations
Medicine, Cardiology, Chemistry +14
Effect of zinc intake on copper excretion and retention in men
MD Festa, HL Anderson, RP Dowdy et al. · American Journal of Clinical Nutrition · 1985 · 89 citations · Full text