Aromatase gene expression and its exon I usage in human breast tumors. Detection of aromatase messenger RNA by reverse transcription-polymerase chain reaction

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

John M. Chirgwin, Alan Przybyla, Raymond J. MacDonald et al. · Biochemistry · 1979 · 22.2K citations

Life Sciences, Biochemistry, Molecular Biology +9

Expression of Transforming Growth Factor α and its Messenger Ribonucleic Acid in Human Breast Cancer: Its Regulation by Estrogen and its Possible Functional Significance

Susan E. Bates, Nancy E. Davidson, Eva M. Valverius et al. · Molecular Endocrinology · 1988 · 435 citations · Full text

Medicine, Endocrinology, Oncology +11

Tissue-specific expression of the human aromatase cytochrome P-450 gene by alternative use of multiple exons 1 and promoters, and switching of tissue-specific exons 1 in carcinogenesis.

Nobuhiro Harada, Toshiaki Utsumi, Y. Takagi · Proceedings of the National Academy of Sciences · 1993 · 361 citations

Life Sciences, Genetics, Molecular Biology +13

A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription.

S E Bulun, Thomas M Price, Mala Mahendroo et al. · The Journal of Clinical Endocrinology & Metabolism · 1993 · 336 citations

Life Sciences, Cancer Biology, Endocrinology +17

Tissue-specific and hormonally controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue.

Mala Mahendroo, Carole R. Mendelson, E R Simpson · Journal of Biological Chemistry · 1993 · 306 citations · Full text

Life Sciences, Genetics, Molecular Biology +17