Aromatase gene expression and its exon I usage in human breast tumors. Detection of aromatase messenger RNA by reverse transcription-polymerase chain reaction

Changbao Zhou, Dujin Zhou, José Miguel Esteban López-Jamar, +4

The Journal of Steroid Biochemistry and Molecular Biology

Tumor BiologyHuman Breast TumorsBreast OncologyEndocrine-related CancerMedicine +10

Molecular Basis for the Aromatization Reaction and Exemestane-Mediated Irreversible Inhibition of Human Aromatase

Yanyan Hong, Bin Yu, Mark A. Sherman, +3

Molecular Endocrinology

Exemestane-mediated Irreversible InhibitionMetabolomic ProfilingMolecular BiologySecondary MetaboliteChemical Biology +15

Autocrine and paracrine actions of breast tumor aromatase. A three-dimensional cell culture study involving aromatase transfected MCF-7 and T-47D cells

Xiu-Zhu Sun, Dujin Zhou, Shiuan Chen

The Journal of Steroid Biochemistry and Molecular Biology

Paracrine ActionsBreast OncologyEndocrine-related CancerMedicineT-47d Cells +8

PNRC: A Proline-Rich Nuclear Receptor Coregulatory Protein That Modulates Transcriptional Activation of Multiple Nuclear Receptors Including Orphan Receptors SF1 (Steroidogenic Factor 1) and ERRα1 (Estrogen Related Receptor α-1)

Dujin Zhou, Keith M. Quach, Chun Yang, +3

Molecular Endocrinology

Biochemical and Biological Characterization of a Novel Anti-aromatase Coumarin Derivative

Shiuan Chen, Michael Cho, Kimberly Karlsberg, +2

Journal of Biological Chemistry

Molecular PharmacologyBiochemistryMedicineBreast Cancer CellsEstrogen Receptor +12

Molecular Basis for the Constitutive Activity of Estrogen-related Receptor α-1

Shiuan Chen, Dujin Zhou, Chun Yang, +1

Journal of Biological Chemistry

SGK3 Is an Estrogen-Inducible Kinase Promoting Estrogen-Mediated Survival of Breast Cancer Cells

Yuan-Zhong Wang, Dujin Zhou, Sheryl Phung, +3

Molecular Endocrinology

Breast OncologyCell DeathCancer BiologyMammary Gland DevelopmentTumor Biology +16

PNRC2 is a 16 kDa coactivator that interacts with nuclear receptors through an SH3-binding motif

Dujin Zhou, Shiuan Chen

Nucleic Acids Research

Molecular Basis of the Catalytic Differences among DT-diaphorase of Human, Rat, and Mouse

Shiuan Chen, Richard J. Knox, Kebin Wu, +4

Journal of Biological Chemistry

Bioorganic ChemistryAldo-keto ReductaseCatalytic DifferencesMolecular BiologyRat Enzyme +16

Aromatase deficiency in a Chinese adult man caused by novel compound heterozygous CYP19A1 mutations: Effects of estrogen replacement therapy on the bone, lipid, liver and glucose metabolism

Zhike Chen, Ou Wang, Min Nie, +8

Molecular and Cellular Endocrinology

Metabolic SyndromeUrologyEndocrine MechanismMedicineChinese Adult Man +10