Sugar modified oligonucleotides: Synthesis, nuclease resistance and base pairing of oligodeoxynucleotides containing 1-(4′-thio-β-d-ribofuranosyl)-thymine

The automated chemical synthesis of long oligoribuncleotides using 2'-O-silylated ribonucleoside 3'-O-phosphoramidites on a controlled-pore glass support: synthesis of a 43-nucleotide sequence similar to the 3'-half molecule of an Escherichia coli formylmethionine tRNA

Nassim Usman, Kelvin K. Ogilvie, Mingzhu Jiang et al. · Journal of the American Chemical Society · 1987 · 367 citations

Pharmacy, Molecular Biology, Bioorthogonal Chemistry +11

Automated solid-phase synthesis, separation, and stereochemistry of phosphorothioate analogs of oligodeoxyribonucleotides

Wojciech J. Stec, Gerald Zon, William Egan · Journal of the American Chemical Society · 1984 · 275 citations

Natural Sciences, Chemistry, Bioorthogonal Chemistry +10

Inhibition of vesicular stomatitis virus protein synthesis and infection by sequence-specific oligodeoxyribonucleoside methylphosphonates

Cheryl H. Agris, Kathleen R. Blake, Paul S. Miller et al. · Biochemistry · 1986 · 150 citations

Life Sciences, Biochemistry, Molecular Biology +14

Α-DNA II. Synthesis of unnatural Α-anomeric oligodeoxyribonucleotides containing the four usual bases and study of their substrate activities for nucleases

F. Morvan, Bernard Rayner, Jean‐Louis Imbach et al. · Nucleic Acids Research · 1987 · 131 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +13

Hybridization arrest of globin synthesis in rabbit reticulocyte lysates and cells by oligodeoxyribonucleoside methylphosphonates

Kathleen R. Blake, Akira Murakami, Sharon A. Spitz et al. · Biochemistry · 1985 · 126 citations

Life Sciences, Biochemistry, Molecular Biology +5