Concepedia

The Ku-dependent non-homologous end-joining but not other repair pathway is inhibited by high linear energy transfer ionizing radiation

Hongyan Wang, Xiang Wang, Piyan Zhang, Ya Wang

DNA repair · 2008 · 118 citations · 33 references

DOI

Concepts

References

33

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Helen E. Bryant, Niklas Schultz, Huw D. Thomas et al. · Nature · 2005 · 5.2K citations

, , +12

Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

John R. Walker, Richard A. Corpina, Jonathan M. Goldberg · Nature · 2001 · 1.2K citations

, , +14

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

Minli Wang, Wei‐Zhong Wu, Wenqi Wu et al. · Nucleic Acids Research · 2006 · 800 citations · Full text

, , +17

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease.

Z Q Wang, B. Auer, Laura Stingl et al. · Genes & Development · 1995 · 779 citations · Full text

, , +8

Involvement of Poly(ADP-ribose) Polymerase-1 and XRCC1/DNA Ligase III in an Alternative Route for DNA Double-strand Breaks Rejoining

Marc Audebert, Bernard Salles, Patrick Calsou · Journal of Biological Chemistry · 2004 · 683 citations · Full text

, , +17