Clinical and laboratory characteristics in the families with diabetes and a mitochondrial tRNALEU(UUR) gene mutation

Sequence and organization of the human mitochondrial genome

Stephen K. Anderson, Alan T. Bankier, B. G. Barrell et al. · Nature · 1981 · 9.7K citations

Medicine, Genetics, Molecular Genetics +12

Insulin Resistance and Insulin Secretory Dysfunction as Precursors of Non-Insulin-Dependent Diabetes Mellitus: Prospective Studies of Pima Indians

Stephen Lillioja, David M. Mott, Maximilian Spraul et al. · New England Journal of Medicine · 1993 · 1.5K citations · Full text

Medicine, Endocrinology, Diabetology +14

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNALys mutation

John M. Shoffner, Marie T. Lott, Angela Maria Serena Lezza et al. · Cell · 1990 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +16

Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

J. M. W. van den Ouweland, H.H.P.J. Lemkes, W. Ruitenbeek et al. · Nature Genetics · 1992 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +15

A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues.

Gino Cortopassi, Darryl Shibata, Nay-Wei Soong et al. · Proceedings of the National Academy of Sciences · 1992 · 640 citations · Full text

Education, Genetics, Molecular Genetics +14