J. M. W. van den Ouweland

Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

J. M. W. van den Ouweland, H.H.P.J. Lemkes, W. Ruitenbeek et al. · Nature Genetics · 1992 · 1.1K citations

Genetic Determinant, Mendelian Disorder, Genetic Disorder +9

Diabetes-associated mitochondrial DNA mutation A3243G impairs cellular metabolic pathways necessary for beta cell function

PM. Andrade, Francesca Frigerio, J. M. W. van den Ouweland et al. · Diabetologia · 2006 · 98 citations · Full text

Metabolic Syndrome, Cellular Metabolic Pathways, Mitochondrial Function +11

Functional and morphological abnormalities of mitochondria harbouring the tRNA Leu(UUR) mutation in mitochondrial DNA derived from patients with maternally inherited diabetes and deafness (MIDD) and progressive kidney disease

J. M. W. van den Ouweland, Pierre Maechler, Claes B. Wollheim et al. · Diabetologia · 1999 · 92 citations · Full text

Mitochondrial Biogenesis, Mitochondrial Function, Morphological Abnormalities +10

Mutations In mitochondrial tRNA genes: non-linkage with syndromes of Wolfram and chronic progressive external ophthalmoplegiaa

J. M. W. van den Ouweland, G.J. Bruining, Dick Lindhout et al. · Nucleic Acids Research · 1992 · 56 citations · Full text

Susceptibility to virus infection of transgenic tobacco plants expressing structural and nonstructural genes of tobacco rattle virus

Gerco C. Angenent, J. M. W. van den Ouweland, John F. Bol · Virology · 1990 · 42 citations

Biology, Tobacco Rattle Virus, Engineering +13