Concepedia

Mechanisms of thymidine kinase/ganciclovir and cytosine deaminase/ 5-fluorocytosine suicide gene therapy-induced cell death in glioma cells

Ute Fischer, Sabine Steffens, Susanne Frank, Nikolai G. Rainov, Klaus Schulze‐Osthoff, Christof M Kramm

Oncogene · 2004 · 102 citations · 38 references

DOI

Concepts

References

38

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

, , +10

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki Miyashita, John C. Reed · Cell · 1995 · 4.1K citations · Full text

, , +12

Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations

, , +10

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

, , +10

Conversion of Bcl-2 to a Bax-like Death Effector by Caspases

Emily H. Cheng, David G. Kirsch, Rollie J. Clem et al. · Science · 1997 · 1.1K citations

, , +16