Concepedia

Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency

Marc Teunis, Emanuela Corsini, Mieke Smits, Charlotte Bernhard Madsen, Tobias Eltze, Janine Ezendam, Valentina Galbiati, Eric R. Gremmer, Cyrille Krul, Annette Landin,

Toxicology in Vitro · 2012 · 47 citations · 24 references

DOI

Concepts

References

24

Use of MTT colorimetric assay to measure cell activation

Denis Gerlier, Nicole Thomasset · Journal of Immunological Methods · 1986 · 1.2K citations

, , +9

A Modular Approach to the ECVAM Principles on Test Validity

Thomas Härtung, Susanne Bremer, Silvia Casati et al. · Alternatives to Laboratory Animals · 2004 · 339 citations

, , +11

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro

Roger Emter, Graham Ellis, Andreas Natsch · Toxicology and Applied Pharmacology · 2010 · 332 citations

, , +5

Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH)

Werner Lilienblum, W. Dekant, Heidi Foth et al. · Archives of Toxicology · 2008 · 313 citations

, , +16

Dissection of antigenic and irritative effects of epicutaneously applied haptens in mice. Evidence that not the antigenic component but nonspecific proinflammatory effects of haptens determine the concentration-dependent elicitation of allergic contact dermatitis.

Stephan Grabbe, Meike Steinert, Karsten Mahnke et al. · Journal of Clinical Investigation · 1996 · 156 citations · Full text

, , +14