The Effect of MDR1 (ABCB1) Polymorphism on the Pharmacokinetic of Tacrolimus in Turkish Renal Transplant Recipients

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity <i>in</i> <i>vivo</i>

Sven Hoffmeyer, Oliver Burk, Oliver von Richter et al. · Proceedings of the National Academy of Sciences · 2000 · 2.4K citations

Medicine, Molecular Genetics, Pharmacology +15

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

Dennis A. Hesselink · Clinical Pharmacology & Therapeutics · 2003 · 653 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

Sven Hoffmeyer · Proceedings of the National Academy of Sciences · 2000 · 598 citations

Medicine, Molecular Genetics, Pharmacology +17

The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

Vincent Haufroid, Michel Mourad, Val rie Van Kerckhove et al. · Pharmacogenetics · 2004 · 445 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome p4503A5 and p-glycoprotein correlate with dose requirement

Iain MacPhee, Salim Fredericks, Tracy W Tai et al. · Transplantation · 2002 · 314 citations

Pharmacy, Pharmacokinetics, Pharmacology +17