Intracellular delivery of purine nucleoside phosphorylase (PNP) fused to protein transduction domain corrects PNP deficiency in vitro

In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse

Steven R. Schwarze, Alan L. Ho, Adamina Vocero-Akbani et al. · Science · 1999 · 2.4K citations

Pharmacy, Biotechnology, Molecular Biology +15

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis

Jehangir S. Wadia, Radu V. Stan, Steven F. Dowdy · Nature Medicine · 2004 · 1.6K citations

Life Sciences, Biochemistry, Molecular Biology +16

A TECHNIQUE FOR ULTRACRYOTOMY OF CELL SUSPENSIONS AND TISSUES

K. T. Tokuyasu · The Journal of Cell Biology · 1973 · 1.1K citations · Full text

Medicine, Cell Biology, Cellular Pathology +14

Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase

Nancy J. Ganson, Susan J. Kelly, Edna Scarlett et al. · Arthritis Research & Therapy · 2005 · 343 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

Purine Nucleoside Phosphorylase Deficiency

M. Louise Markert · SpringerReference · 2012 · 245 citations

Life Sciences, Genetics, Immunology +13