Concepedia

Methylation of the O<sup>6</sup>Position of Guanine in DNA is the Most Likely Initiating Event in Carcinogenesis by Methylating Agents

Anthony E. Pegg

Cancer Investigation · 1984 · 236 citations · 19 references

DOI

Concepts

Abstract

(1984). Methylation of the O6 Position of Guanine in DNA is the Most Likely Initiating Event in Carcinogenesis by Methylating Agents. Cancer Investigation: Vol. 2, No. 3, pp. 223-231.

References

19

Persistence of <i>O</i> 6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by Ethylnitrosourea

Regine Goth, Manfred F. Rajewsky · Proceedings of the National Academy of Sciences · 1974 · 490 citations · Full text

All oxygens in nucleic acids react with carcinogenic ethylating agents

Brett C. Singer · Nature · 1976 · 310 citations

, , +10

Effect of dimethylnitrosamine on persistence of methylated guanines in rat liver and kidney DNA

John W. Nicoll, Peter Swann, Anthony E. Pegg · Nature · 1975 · 187 citations

, , +7

Purification and properties of O6-methylguanine-DNA transmethylase from rat liver.

Anthony E. Pegg, Laurie Wiest, Robert S. Foote et al. · Journal of Biological Chemistry · 1983 · 183 citations · Full text

, , +4

Comparison of the rates of repair of O6-alkylguanines in DNA by rat liver and bacterial O6-alkylguanine-DNA alkyltransferase.

Anthony E. Pegg, David A. Scicchitano, M. Eileen Dolan · PubMed · 1984 · 86 citations

, , +18