Humanization of an anti-human TNF-α antibody by variable region resurfacing with the aid of molecular modeling

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

Mark A. Bradford · Analytical Biochemistry · 1976 · 225.4K citations

Life Sciences, Biochemistry, Protein Biochemistry +7

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations

Pharmacy, Cell Biology, Immunology +11

Sequences of proteins of immunological interest

Analytical Biochemistry · 1984 · 3.4K citations

Life Sciences, Immunology, Molecular Biology +10

Detection and localization of individual antibody-antigen recognition events by atomic force microscopy.

Peter Hinterdorfer, Werner Baumgärtner, Hermann J. Gruber et al. · Proceedings of the National Academy of Sciences · 1996 · 1.2K citations

Natural Sciences, Bioengineering, Biophysics +17

Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains.

Sherie L. Morrison, M J Johnson, L A Herzenberg et al. · Proceedings of the National Academy of Sciences · 1984 · 1K citations · Full text

Pharmacy, Immunology, Molecular Biology +17