Publication | Open Access

Prediction of dose-hepatotoxic response in humans based on toxicokinetic/toxicodynamic modeling with or without in vivo data: A case study with acetaminophen

Vivo DataHepatologyPredictive ToxicologyPharmacologyHepatitisToxicokinetic/toxicodynamic ModelingCase StudyToxicologyBiostatisticsHepatotoxicityToxicokineticsPharmacodynamic ModelingMedicinePhysiologically-based Pharmacokinetic ModelingDrug Discovery