Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice - Concepedia

Concepedia

Publication | Open Access

Oxaliplatin in combination with liver-specific expression of interleukin 12 reduces the immunosuppressive microenvironment of tumours and eradicates metastatic colorectal cancer in mice

DOI Full Paper Access

110

Citations

38

References

2010

Year

Manuela González-Aparicio, Pilar Alzuguren, Itsaso Mauleón, José Medina‐Echeverz, Sandra Hervás‐Stubbs, Uxua Mancheño, Pedro Berraondo, Julien Crettaz, Gloria González‐Aseguinolaza, Jesús Prìeto,

Abstract

Long-term controlled expression of IL-12 using an HC-Ad vector in combination with oxaliplatin is effective and clinically applicable against hepatic colon cancer metastases.

References

	Year	Citations

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