Concepedia

LRP/Amyloid β-Peptide Interaction Mediates Differential Brain Efflux of Aβ Isoforms

Rashid Deane, Zhenhua Wu, Abhay P. Sagare, Judianne Davis, Shi Du Yan, Katie Hamm, Feng Xu, Margaret Parisi, Barbra LaRue, Hong Wei Hu,

Neuron · 2004 · 829 citations · 51 references

DOIFull text

Open access

Concepts

References

51

Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Dominic M. Walsh, Igor Klyubin, Julia V. Fadeeva et al. · Nature · 2002 · 4.3K citations

, , +14

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Karen Hsiao, Paul F. Chapman, Steven P. Nilsen et al. · Science · 1996 · 4.2K citations

, , +17

Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis

Rakez Kayed, Elizabeth Head, Jennifer L. Thompson et al. · Science · 2003 · 4.1K citations

, , +17

Oligomeric and Fibrillar Species of Amyloid-β Peptides Differentially Affect Neuronal Viability

Karie N. Dahlgren, Arlene M. Manelli, W. Blaine Stine et al. · Journal of Biological Chemistry · 2002 · 1.4K citations · Full text

, , +17

RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

Rashid Deane, Shi Du Yan, Ram Kumar Submamaryan et al. · Nature Medicine · 2003 · 1.4K citations

, , +14