Concepedia

DNA Methylation in Schizophrenia Subjects: Gender and <i>MTHFR</i> 677C/T Genotype Differences

Kyle J. Burghardt, J. Richard Pilsner, Michael J. Bly, Vicki L. Ellingrod

Epigenomics · 2012 · 52 citations · 26 references

DOI

Abstract

TT genotype females had the lowest methylation, which may explain metabolic syndrome gender differences in schizophrenia. Folate supplementation may be a suggested intervention within schizophrenia; however, additional work is required.

References

26

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Debomoy K. Lahiri, John I. Numberger · Nucleic Acids Research · 1991 · 2.3K citations · Full text

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Functional Analysis of Genetic Variation in Catechol-O-Methyltransferase (COMT): Effects on mRNA, Protein, and Enzyme Activity in Postmortem Human Brain

Jingshan Chen, Barbara K. Lipska, Nader D. Halim et al. · The American Journal of Human Genetics · 2004 · 1.7K citations · Full text

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Congruencies in increased mortality rates, years of potential life lost, and causes of death among public mental health clients in eight states.

Craig W. Colton, Ronald W. Manderscheid · PubMed · 2006 · 1.3K citations

Atypical Antipsychotic Drugs and the Risk of Sudden Cardiac Death

Wayne A. Ray, Cecilia P. Chung, Katherine T. Murray et al. · New England Journal of Medicine · 2009 · 1.2K citations · Full text

Prevalence of the metabolic syndrome in patients with schizophrenia: Baseline results from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia trial and comparison with national estimates from NHANES III

Joseph P. McEvoy, Jonathan M. Meyer, Donald Goff et al. · Schizophrenia Research · 2005 · 1.1K citations

, , +11