Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter et al. · Science · 1993 · 9.5K citations

Life Sciences, Genetics, Neurology +17

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

Robert D. Terry, Eliezer Masliah, David P. Salmon et al. · Annals of Neurology · 1991 · 4.4K citations

Medicine, Neurology, Neuroscience +17

Synergistic Effects of Traumatic Head Injury and Apolipoprotein-epsilon4 in Patients With Alzheimer's Disease

Richard Mayeux, Ruth Ottman, Gladys E. Maestre et al. · Neurology · 1995 · 585 citations · Full text

Medicine, Genetics, Neurology +17

Loss of the Presynaptic Vesicle Protein Synaptophysin in Hippocampus Correlates with Cognitive Decline in Alzheimer Disease

Chun‐I Sze, Juan C. Troncoso, Claudia H. Kawas et al. · Journal of Neuropathology & Experimental Neurology · 1997 · 573 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Neurodegeneration in the Central Nervous System of apoE-Deficient Mice

Eliezer Masliah, Margaret Mallory, Nianfeng Ge et al. · Experimental Neurology · 1995 · 407 citations

Life Sciences, Neurobiology, Neuroscience +14