Concepedia

3. Endothelin antagonists: discovery of EMD 122946, a highly potent and orally active ETA selective antagonist

Werner W. K. R. Mederski, Dieter Dorsch, Mathias Osswald, Soheila Anzali, Maria Christadler, C.‐J. SCHMITGES, P. Schelling, Claudia Wilm, Markus Fluck

Bioorganic & Medicinal Chemistry Letters · 1998 · 15 citations · 13 references

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References

13

Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist.

Martine Clozel, Volker Breu, Gillian A. Gray et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 668 citations

, , +15

Venous smooth muscle contains vasoconstrictor ETB-like receptors

Suzanne Moreland, Diane M. McMullen, Carol L. Delaney et al. · Biochemical and Biophysical Research Communications · 1992 · 256 citations

, , +12

A New Method for Continuous Chronic Measurement and Recording of Blood Pressure, Heart Rate and Activity in the Rat Via Radio-telemetry

Brian Brockway, Perry Mills, Silvia H. Azar · Clinical and Experimental Hypertension Part A Theory and Practice · 1991 · 249 citations

, , +17

Pharmacological profile of FR139317, a novel, potent endothelin ETA receptor antagonist.

Keizo Sogabe, Hisataka Nirei, Miwako Shoubo et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 222 citations

, , +13

Pharmacological characterization of A-127722: an orally active and highly potent ETA-selective receptor antagonist.

Terry J. Opgenorth, Andrew Adler, Samuel V. Calzadilla et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 210 citations

, , +15