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SB 242084, a Selective and Brain Penetrant 5-HT 2C Receptor Antagonist

G.A. Kennett, Martyn Wood, Fiona Bright, Brenda Trail, Graham J. Riley, Vicky Holland, Kim Y. Avenell, Tania O. Stean, N. Upton, Steven M. Bromidge,

Neuropharmacology · 1997 · 524 citations · 40 references

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References

40

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

, , +12

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

André DeLÉAN, Peter J. Munson, David Rodbard · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 2.4K citations

, , +17

Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors

Laurence H. Tecott, Linda M. Sun, Susan F. Akana et al. · Nature · 1995 · 1.3K citations

, , +12

Distribution of the serotonin 5-HT2 receptor family mRNAs: comparison between 5-HT2A and 5-HT2C receptors

María Pompeiano, José Palacios, Guadalupe Mengod · Molecular Brain Research · 1994 · 877 citations

, , +13