N. Upton

SB 242084, a Selective and Brain Penetrant 5-HT 2C Receptor Antagonist

G.A. Kennett, Martyn Wood, Fiona Bright et al. · Neuropharmacology · 1997 · 523 citations · Full text

Sb 242084, Molecular Pharmacology, Functional Selectivity +9

Orexin-A, an hypothalamic peptide with analgesic properties

Sharon Bingham, Philip T. Davey, Adam J. Babbs et al. · Pain · 2001 · 266 citations

Pain Medicine, Hypothalamic Peptide Orexin-a, Neuropathic Pain +16

SB‐334867, a selective orexin‐1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin‐A in rats

R.J. Rodgers, Jason C. G. Halford, Ricardo Luiz Nunes‐de‐Souza et al. · European Journal of Neuroscience · 2001 · 230 citations

Food Intake, Behavioural Satiety, Synaptic Signaling +23

Resocialisation of isolation-reared rats does not alter their anxiogenic profile on the elevated X-maze model of anxiety

Ian K. Wright, N. Upton, C.A. Marsden · Physiology & Behavior · 1991 · 178 citations

Experimental Psychopathology, Psychiatry, Behavioral Neuroscience +14

Effect of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze

Ian K. Wright, N. Upton, C.A. Marsden · Psychopharmacology · 1992 · 135 citations

Neurobiological Mechanism, Neuropsychology, Psychiatry +14