Concepedia

Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir

Brian Kirby, Ann C. Collier, Evan D. Kharasch, Vaishali Dixit, Pankaj B. Desai, Dale Whittington, Kenneth E. Thummel, Jashvant D. Unadkat

Drug Metabolism and Disposition · 2011 · 67 citations · 37 references

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References

37

Effect of grapefruit juice on digoxin pharmacokinetics in humans

Laurent Becquemont, Céline Verstuyft, Reinhold Kerb et al. · Clinical Pharmacology & Therapeutics · 2001 · 389 citations

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Polymorphic dextromethorphan metabolism: Co-segregation of oxidative O-demethylation with debrisoquin hydroxylation

B. Schmid, J Bircher, R Preisig et al. · Clinical Pharmacology & Therapeutics · 1985 · 387 citations

, , +12

Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.

Gondi Kumar, A. David Rodrigues, Alex Buko et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 352 citations

, , +17

Mechanism-Based Inactivation of CYP3A by HIV Protease Inhibitors

C. Steven Ernest, Stephen D. Hall, David Jones · Journal of Pharmacology and Experimental Therapeutics · 2005 · 251 citations

, , +17

Metabolism of the human immunodeficiency virus protease inhibitors indinavir and ritonavir by human intestinal microsomes and expressed cytochrome P4503A4/3A5: mechanism-based inactivation of cytochrome P4503A by ritonavir.

T. Koudriakova, Eugenia Iatsimirskaia, Ilya Utkin et al. · PubMed · 1998 · 244 citations

, , +17