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Publication | Open Access

1,2-Dimethylhydrazine-Induced Colon Carcinoma and Lymphoma in msh2-/- Mice

DOIFull Paper Access

50

Citations

37

References

2001

Year

Claudia Colussi, Silvia Fiumicino, Alessandro Giuliani, Sandra Rosini, Piero Musiani, C. Macrì, Christopher S. Potten, Marco Crescenzi, Margherita Bignami
JNCI Journal of the National Cancer Institute

Abstract

Inactivation of msh2 allows the proliferation of gastrointestinal tract cells damaged by methylating agents. Furthermore, MMR constitutes a powerful defense against colorectal cancer induced by DNA methylation.

References

YearCitations

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