Isothiocyanate‐rich <i>Moringa oleifera</i> extract reduces weight gain, insulin resistance, and hepatic gluconeogenesis in mice

Abstract

Data suggest that MICs are the main anti-obesity and anti-diabetic bioactives of MC, and that they exert their effects by inhibiting rate-limiting steps in liver gluconeogenesis resulting in direct or indirect increase in insulin signaling and sensitivity. These conclusions suggest that MC may be an effective dietary food for the prevention and treatment of obesity and type 2 diabetes.