Concepedia

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

Jaime M. Ross, James B. Stewart, Erik Hagström, Stefan Brené, Arnaud Mourier, Giuseppe Coppotelli, Christoph Freyer, Marie Lagouge, Barry J. Hoffer, Nils‐Göran Larsson

Nature · 2013 · 277 citations · 25 references

DOI

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25

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Aleksandra Trifunović, Anna Wredenberg, Maria Falkenberg et al. · Nature · 2004 · 2.7K citations

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Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging

Gregory C. Kujoth, Asimina Hiona, Thomas D. Pugh et al. · Science · 2005 · 2.2K citations

, , +17

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

Marisol Corral‐Debrinski, Terzah M. Horton, Marie T. Lott et al. · Nature Genetics · 1992 · 886 citations

, , +16

Detection of a specific mitochondrial DNA deletion in tissues of older humans

Gino Cortopassi, Norman Arnheim · Nucleic Acids Research · 1990 · 792 citations · Full text

, , +7

ON THE NATURE OF THE AGING PROCESS

Leo Szilard · Proceedings of the National Academy of Sciences · 1959 · 645 citations · Full text

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