Christoph Freyer

Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA

James B. Stewart, Christoph Freyer, Joanna L. Elson et al. · PLoS Biology · 2008 · 535 citations · Full text

Life Sciences, Evolutionary Biology, Genetics +13

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development

Jaime M. Ross, James B. Stewart, Erik Hagström et al. · Nature · 2013 · 277 citations

Life Sciences, Genetics, Molecular Genetics +14

Integration of whole genome sequencing into a healthcare setting: high diagnostic rates across multiple clinical entities in 3219 rare disease patients

Henrik Stranneheim, Kristina Lagerstedt‐Robinson, Måns Magnusson et al. · Genome Medicine · 2021 · 271 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Ultra-Deep Sequencing of Mouse Mitochondrial DNA: Mutational Patterns and Their Origins

Adam Ameur, James B. Stewart, Christoph Freyer et al. · PLoS Genetics · 2011 · 200 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication

Dusanka Milenkovic, Sanja Matić, Inge Kühl et al. · Human Molecular Genetics · 2013 · 170 citations · Full text

Life Sciences, Genetics, Molecular Biology +17