Effect of long-term cyclic mechanical load on protein synthesis and morphological changes in cultured Myocardial cells from neonatal rat

Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy.

Junichi Sadoshima, L. Jahn, Toshiyuki Takahashi et al. · Journal of Biological Chemistry · 1992 · 606 citations · Full text

Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activation.

Issei Komuro, Youichi Katoh, T Kaida et al. · Journal of Biological Chemistry · 1991 · 436 citations · Full text

Cardiac Muscle, Muscle Function, Specific Gene Expression +21

Myocyte hypertrophy in neonatal rat heart cultures and its regulation by serum and by catecholamines.

Paul Simpson, Aiden McGrath, Shoshana Savion · Circulation Research · 1982 · 422 citations

Cardiac Muscle, Heart Failure, Myocardial Cell Hypertrophy +18

A new vacuum-operated stress-providing instrument that applies static or variable duration cyclic tension or compression to cells <i>in vitro</i>

Albert J. Banes, Jerome A. Gilbert, D.F. Taylor et al. · Journal of Cell Science · 1985 · 406 citations

Osteoblasts increase their rate of division and align in response to cyclic, mechanical tension in vitro.

Mortimer J. Buckley, A J Banes, L G Levin et al. · PubMed · 1988 · 269 citations