Nanomedicine · 2008 · 223 citations · 57 references
PharmacyPharmaceuticsPharmacologyDrug DeliveryNanomaterialsTargeted Drug DeliveryCancer NanomedicineNanomaterials For Drug DeliveryNanomedicineNanoparticle Delivery SystemsNanoparticle DesignNanoparticle FormulationsDrug Delivery NanocarriersMagnetic MicellesMagnetic NanoparticlesMicellesMultifunctional NanoparticlesNanoparticlesPolymeric MicellesTargeted Delivery
Novel technology in the nanomedicine field is expected to develop innovative products as targeted drug-delivery approaches. Targeted drug delivery of various drugs for the treatment of cancer, AIDS and brain disorders is the primary research area in which nanomedicines have a major role and need. This review is concerned with emerging targeted nanomedicines (polymeric nanoparticles, solid lipid nanoparticles, polymeric micelles, dendrimers, liposomes, gold nanoparticles and magnetic nanoparticles) and multifunctional carriers capable of combining targeted drug delivery and imaging (polymeric micelles, dendrimers and magnetic nanoparticles) in the field of pharmaceutical applications. The significant toxicity issues associated with these nanomedicines are also explored here.
57
Biodegradable Long-Circulating Polymeric Nanospheres
Ruxandra Gref, Yoshiharu Minamitake, Maria Teresa Peracchia et al. · Science · 1994 · 2.9K citations
Gold Nanoparticles Are Taken Up by Human Cells but Do Not Cause Acute Cytotoxicity
Ellen E. Connor, Judith N. Mwamuka, Anand Gole et al. · Small · 2005 · 2.4K citations
The Role of Mononuclear Phagocytes in HTLV-III/LAV Infection
Suzanne Gartner, P Markovits, David M. Markovitz et al. · Science · 1986 · 1.8K citations
Multifunctional Polymeric Micelles as Cancer-Targeted, MRI-Ultrasensitive Drug Delivery Systems
Norased Nasongkla, Erik A. Bey, Jimin Ren et al. · Nano Letters · 2006 · 1.2K citations
Pharmacy, Oncology, Pharmaceutics +17