Therapeutic Efficacy of Astatine-211–Labeled Trastuzumab on Radioresistant SKOV-3 Tumors in Nude Mice

Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets

Raphael Clynes, Terri L. Towers, Leonard G. Presta et al. · Nature Medicine · 2000 · 2.7K citations

Medicine, Cancer Biology, Oncology +15

Determination of the immunoreactive function of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess

Tore Lindmo, Epie Boven, Frank Cuttitta et al. · Journal of Immunological Methods · 1984 · 937 citations

Pharmacy, Immunology, Monoclonal Antibodies +13

Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells.

Jordi Codony‐Servat, Joan Albanell, Federico Rojo et al. · PubMed · 2001 · 775 citations

Medicine, Molecular Biology, Oncology +16

Evaluation of Monoclonal Humanized Anti-HER2 Antibody, Trastuzumab, in Patients With Recurrent or Refractory Ovarian or Primary Peritoneal Carcinoma With Overexpression of HER2: A Phase II Trial of the Gynecologic Oncology Group

Michael A. Bookman, Kathleen M. Darcy, Daniel L. Clarke‐Pearson et al. · Journal of Clinical Oncology · 2003 · 613 citations

Medicine, Gynecology, Oncology +17

Sensitization of breast cancer cells to radiation by trastuzumab.

Ke Liang, Yang Lü, Weidong Jin et al. · PubMed · 2003 · 245 citations

Medicine, Oncology, Radiation Oncology +17