Point substitutions in a promoter-like region and the V1 gene affect the host range and symptoms of maize streak virus

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

A comprehensive set of sequence analysis programs for the VAX

John Devereux, Paul Haeberli, Oliver Smithies · Nucleic Acids Research · 1984 · 14.4K citations · Full text

Life Sciences, Bioinformatics, Genetics +8

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

Frederick Sanger, Alan Coulson, B. G. Barrell et al. · Journal of Molecular Biology · 1980 · 3.5K citations

Life Sciences, Microbiology, Molecular Biology +12

Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template

Mark J. Zoller, Michael J. Smith · DNA · 1984 · 906 citations

Life Sciences, Genetics, Molecular Biology +15

An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences

Rodger Staden · Nucleic Acids Research · 1982 · 798 citations · Full text

Life Sciences, Bioinformatics, Visualization +15