Concepedia

Parallel solid-phase synthesis of vitronectin receptor (αvβ3) inhibitors

Ariamala Gopalsamy, Hui Yang, John W. Ellingboe, Kenneth L. Kees, Jeanne Yoon, Richard J. Murrills

Bioorganic & Medicinal Chemistry Letters · 2000 · 11 citations · 12 references

DOI

Concepts

References

12

Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Peter C. Brooks, Anthony M.P. Montgomery, Mauricio Rosenfeld et al. · Cell · 1994 · 2.3K citations

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Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen.

A M Montgomery, R. Reisfeld, David A. Cheresh · Proceedings of the National Academy of Sciences · 1994 · 446 citations

, , +17

Role of the alpha v beta 3 integrin in human melanoma cell invasion.

Richard E.B. Seftor, Elisabeth A. Seftor, Kurt R. Gehlsen et al. · Proceedings of the National Academy of Sciences · 1992 · 418 citations

, , +17

The osteoclast functional antigen, implicated in the regulation of bone resorption, is biochemically related to the vitronectin receptor.

J. Michael Davies, J Warwick, Nick Totty et al. · The Journal of Cell Biology · 1989 · 367 citations · Full text

, , +17

Design, Synthesis, and Evaluation of Small-Molecule Libraries

Jonathan A. Ellman · Accounts of Chemical Research · 1996 · 288 citations

, , +9