Concepedia

Development of energetic pharmacophore for the designing of 1,2,3,4-tetrahydropyrimidine derivatives as selective cyclooxygenase-2 inhibitors

Deepak K. Lokwani, Reecha D. Shah, Santosh N. Mokale, Padma Shastry, Devanand B. Shinde

Journal of Computer-Aided Molecular Design · 2012 · 19 citations · 23 references

DOI

Concepts

References

23

Extra Precision Glide:  Docking and Scoring Incorporating a Model of Hydrophobic Enclosure for Protein−Ligand Complexes

Richard A. Friesner, Robert B. Murphy, Matthew P. Repasky et al. · Journal of Medicinal Chemistry · 2006 · 6.9K citations

, , +16

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

Andrew C. Wallace, Roman A. Laskowski, Janet M. Thornton · Protein Engineering Design and Selection · 1995 · 5.7K citations

, , +14

Cardiovascular Events Associated with Rofecoxib in a Colorectal Adenoma Chemoprevention Trial

Robert S. Bresalier, Robert S. Sandler, Hui Quan et al. · New England Journal of Medicine · 2005 · 2.5K citations · Full text

, , +8

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain.

Karen Seibert, Y Zhang, K. Leahy et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations

, , +17

Coxibs and Cardiovascular Disease

Garret A. FitzGerald · New England Journal of Medicine · 2004 · 896 citations

, , +15