Excision of the oxidatively formed 5-hydroxyhydantoin and 5-hydroxy-5-methylhydantoin pyrimidine lesions by Escherichia coli and Saccharomyces cerevisiae DNA N-glycosylases

Human DNA Repair Genes

Richard D. Wood, Michael Mitchell, John Sgouros et al. · Science · 2001 · 1.5K citations

Life Sciences, Genetics, Molecular Biology +15

Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily

Huw M. Nash, Steven D. Bruner, Orlando D. Schärer et al. · Current Biology · 1996 · 436 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine.

Patricia Auffret van der Kemp, Dominique Thomas, Régine Barbey et al. · Proceedings of the National Academy of Sciences · 1996 · 366 citations

Life Sciences, Genetics, Microbiology +11

Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/apyrimidinic sites.

Serge Boiteux, Timothy O’Connor, Florence Lederer et al. · Journal of Biological Chemistry · 1990 · 349 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase.

Zafer Hatahet, Yoke W. Kow, Andrei A. Purmal et al. · Journal of Biological Chemistry · 1994 · 341 citations · Full text

Life Sciences, Genetics, Molecular Biology +11