Andrei A. Purmal

New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase.

Zafer Hatahet, Yoke W. Kow, Andrei A. Purmal et al. · Journal of Biological Chemistry · 1994 · 341 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

Curaxins: Anticancer Compounds That Simultaneously Suppress NF-κB and Activate p53 by Targeting FACT

Alexander V. Gasparian, Catherine A. Burkhart, Andrei A. Purmal et al. · Science Translational Medicine · 2011 · 245 citations · Full text

Medicine, Cancer Biology, Oncology +10

Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing<i>in vitro</i>

Andrei A. Purmal, Yoke W. Kow, Susan S. Wallace · Nucleic Acids Research · 1994 · 160 citations · Full text

Life Sciences, Genetics, Microbiology +5

Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma

Daniel R. Carter, Jayne Murray, Belamy B. Cheung et al. · Science Translational Medicine · 2015 · 151 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Small-Molecule Multidrug Resistance–Associated Protein 1 Inhibitor Reversan Increases the Therapeutic Index of Chemotherapy in Mouse Models of Neuroblastoma

Catherine A. Burkhart, Fujiko Watt, Jayne Murray et al. · Cancer Research · 2009 · 118 citations · Full text

Medicine, Oncology, Pharmacology +15