THE INFLUENCE OF THE FOODSTUFFS UPON THE SUSCEPTIBILITY OF THE LIVER TO INJURY BY CHLOROFORM, AND THE PROBABLE MECHANISM OF THEIR ACTION 12

Abstract

In a previous publication, data were presented which show that anesthesia produced by the in- halation of chloroform or divinyl ether, volatilized by a stream of oxygen, results in much less dam- age to the liver of the dog than when air is used as the volatilizing agent (1). Evidence already presented (2) reveals, in the dog, no difference in the rate or the degree of discharge of hepatic glvcogen, or the height to which the blood sugar rises, or the amount of fatty infiltration, when the chloroform is volatilized with air or with oxygen, provided a very marked anoxemia does not exist. The protective action of oxygen appears not to be associated with these metabolic changes.