Concepedia

Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers

Shingo Nakahata, Tomonaga Ichikawa, Phudit Maneesaay, Yusuke Saito, Kentaro Nagai, Tomohiro Tamura, Nawin Manachai, Norio Yamakawa, Makoto Hamasaki, Issay Kitabayashi,

Nature Communications · 2014 · 162 citations · 47 references

DOIFull text

Open access

Concepts

References

47

<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

, , +16

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Peter A. Steck, Mark A. Pershouse, Samar A. Jasser et al. · Nature Genetics · 1997 · 2.8K citations

, , +11

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

Corinna Bialojan, Akira Takai · Biochemical Journal · 1988 · 1.7K citations · Full text

, , +16

Phosphorylation of the PTEN Tail Regulates Protein Stability and Function

Francisca Vázquez, Shivapriya Ramaswamy, Noriaki Nakamura et al. · Molecular and Cellular Biology · 2000 · 781 citations

, , +17

Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression

Lloyd C. Trotman, Xinjiang Wang, Andrea Alimonti et al. · Cell · 2007 · 748 citations · Full text

, , +13