Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

Corinna Bialojan, Akira Takai

Biochemical Journal

Bioorganic ChemistryType 2CProtein PhosphatasesType 2BCellular Physiology +14

Regulation of Ca2+ -dependent K+ -channel activity in tracheal myocytes by phosphorylation

Hiroaki Kume, Akira Takai, H Tokuno, +1

Nature

Cardiac MuscleSignal TransductionMolecular PhysiologyCell SignalingPhysiology +8

Smooth muscle myosin phosphatase inhibition and force enhancement by black sponge toxin

Akira Takai, Corinna Bialojan, Monika Troschka, +1

FEBS Letters

Muscle FunctionSmooth Muscle ContractionCytoskeletonMechanotransductionCellular Physiology +15

Effects of a protein phosphatase inhibitor, okadaic acid, on membrane currents of isolated guinea-pig cardiac myocytes

J. Hescheler, Gottfried Mieskes, J. C. Rüegg, +2

Pflügers Archiv - European Journal of Physiology

Cardiac MuscleCardiomyopathyOkadaic AcidMolecular PhysiologyBiochemistry +11

Inhibitory effect of okadaic acid derivatives on protein phosphatases. A study on structure-affinity relationship

Akira Takai, Michio Murata, Koichiro Torigoe, +3

Biochemical Journal

Type 1Pharmaceutical ChemistryBioorganic ChemistryBiochemistryCircular Conformation +13

Inhibitory effect of okadaic acid on the <i>p</i>-nitrophenyl phosphate phosphatase activity of protein phosphatases

Akira Takai, Gottfried Mieskes

Biochemical Journal

Type 2AType 1Okadaic AcidCellular EnzymologyBiochemistry +12

Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C.

Gregory P. Downey, C K Chan, Peter J. Lea, +2

The Journal of Cell Biology

Cell AdhesionMembrane RufflingCytoskeletonCellular PhysiologyCell Signaling +14

Comparison of protein phosphatase inhibitory activity and apparent toxicity of microcystins and related compounds

Emiko Ito, Akira Takai, Fumio Kondo, +3

Toxicon

BiochemistryMedicineApparent ToxicityToxicologyRelated Compounds +3

Inhibition of specific binding of okadaic acid to protein phosphatase 2A by microcystin-LR, calyculin-A and tautomycin: method of analysis of interactions of tight-binding ligands with target protein

Akira Takai, Kento Sasaki, Hiroshi Nagai, +4

Biochemical Journal

Bioorganic ChemistryAldo-keto ReductaseDissociation ConstantMolecular BiologyChemical Biology +19

Okadaic acid, a phosphatase inhibitor, induces activation and phosphorylation of the Na+/H+ antiport

Laurence Bianchini, Michael Woodside, Claude Sardet, +3

Journal of Biological Chemistry

Cellular PhysiologyOxidative StressSignaling PathwayReceptor Tyrosine KinaseNa+/h+ Antiport +18