Experimental Biology and Medicine · 1954 · 238 citations · 0 references
AgricultureNutritionNutritional SciencesHuman NutritionLipid BiochemistryMacronutrient MetabolismAdipose TissueFatty Acid MetabolismLipid AnalysisLipid MetabolismLipid NutritionWeight ManagementAnimal FatsDietary Fat EffectsDietary Fat ModificationExogenous FeedingFat SubstitutesFats IntakeLipid Response To Diet
Six subjects with obesity of exogenous origin showed significant reductions in serum concentrations of free and esterified cholesterol and of phospholipids when plant fats were substituted isocalorically for animal fats during a 4-month metabolic ward study. The approximate magnitude of the change was 20% decrease. Neutral fat levels showed no significant change. Body weights and caloric intakes were held constant throughout the experiment.