Concepedia

Enantiopure Tetrahydro-β-carbolines via Pictet−Spengler Reactions with <i>N</i>-Sulfinyl Tryptamines

Christiaan Gremmen, Bianca Willemse, Martin J. Wanner, Gerrit‐Jan Koomen

Organic Letters · 2000 · 76 citations · 20 references

DOI

Concepts

Abstract

The influence of N-sulfinyl chiral auxiliaries on the stereochemistry of the Pictet-Spengler reaction has been investigated. From enantiopure (R)-N-p-toluenesulfinyltryptamine a new and efficient route to enantiopure tetrahydro-beta-carbolines has been established.

References

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