In Vitro-Reconstituted Nucleoids Can Block Mitochondrial DNA Replication and Transcription

Mitochondrial transcription factor A is necessary for mtDNA maintance and embryogenesis in mice

Nils‐Göran Larsson, Jianming Wang, Hans Wilhelmsson et al. · Nature Genetics · 1998 · 1.6K citations

Developmental Biology, Mitochondrial Biogenesis, Mitochondrial Function +9

Mitochondrial transcription factor A regulates mtDNA copy number in mammals

Mats I. Ekstrand · Human Molecular Genetics · 2004 · 903 citations · Full text

Dna, Genetics, Genomic Mechanism +18

Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA

Maria Falkenberg, Martina Gaspari, Anja Rantanen et al. · Nature Genetics · 2002 · 596 citations

Chromatin, Transcriptional Regulation, Mitochondrial Biogenesis +9

Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA

Christian Kukat, Christian A. Wurm, Henrik Spåhr et al. · Proceedings of the National Academy of Sciences · 2011 · 546 citations

Dna, Mitochondrial Dysfunction, Genetics +18

The Mitochondrial Transcription Factor TFAM Coordinates the Assembly of Multiple DNA Molecules into Nucleoid-like Structures

Brett A. Kaufman, Nela Durisic, Jeffrey M. Mativetsky et al. · Molecular Biology of the Cell · 2007 · 413 citations · Full text