PEG-transferrin conjugated TRAIL (TNF-related apoptosis-inducing ligand) for therapeutic tumor targeting

Safety and antitumor activity of recombinant soluble Apo2 ligand

Avi Ashkenazi, Roger Pai, Sharon Fong et al. · Journal of Clinical Investigation · 1999 · 2.2K citations · Full text

Medicine, Oncology, Pharmacology +17

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

Minji Jo, Tae‐Hyoung Kim, Dai‐Wu Seol et al. · Nature Medicine · 2000 · 844 citations

Life Sciences, Pathology, Pharmacology +12

Preclinical Studies to Predict the Disposition of Apo2L/Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand in Humans: Characterization of in Vivo Efficacy, Pharmacokinetics, and Safety

Sean K. Kelley, Louise A. Harris, David Xie et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 443 citations

Life Sciences, Oncology, Pharmacology +17

Novel Shielded Transferrin−Polyethylene Glycol−Polyethylenimine/DNA Complexes for Systemic Tumor-Targeted Gene Transfer

Malgorzata Kursa, Greg F. Walker, Vanessa Roessler et al. · Bioconjugate Chemistry · 2002 · 311 citations

Pharmacy, Oncology, Pharmaceutics +17

Decreased Binding to Proteins and Cells of Polymeric Gene Delivery Vectors Surface Modified with a Multivalent Hydrophilic Polymer and Retargeting through Attachment of Transferrin

Philip R. Dash, Martin L. Read, Kerry Fisher et al. · Journal of Biological Chemistry · 2000 · 160 citations · Full text

Pharmacy, Bioengineering, Pharmaceutics +17