Growth inhibition of virus transformed cells in vitro and antitumor activity in vivo of geldanamycin and its derivatives.

GELDANAMYCIN, A NEW ANTIBIOTIC

C. DeBoer, P. A. MEULMAN, Richard J. Wnuk et al. · The Journal of Antibiotics · 1970 · 467 citations · Full text

Life Sciences, Medicinal Chemistry, Microbiology +5

Tumor inhibitors. LXXIII. Maytansine, a novel antileukemic ansa macrolide from Maytenus ovatus

S. Morris Kupchan, Yasuo Komoda, William A. Court et al. · Journal of the American Chemical Society · 1972 · 432 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Ansamitocin, a group of novel maytansinoid antibiotics with antitumour properties from Nocardia

Eiji Higashide, Mitsuko Asai, Koichiro Ootsu et al. · Nature · 1977 · 213 citations

Medicine, Microbiology, Pharmacology +5

Geldanamycin. I. Structure assignment

Kenneth L. Rinehart, Kazuya Sasaki, George Slomp et al. · Journal of the American Chemical Society · 1970 · 121 citations

Pharmacy, Chemistry, Medicinal Chemistry +6

Isolation and characterization of temperature-sensitive mutants of Simian Virus 40

Genki Kimura, Renato Dulbecco · Virology · 1972 · 96 citations

Life Sciences, Microbiology, Molecular Biology +10