Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity

References

Page 1

	Year	Citations
Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment Thomas J. Wickham, Patricia Mathias, David A. Cheresh, Cell Molecular VirologyPathogenesisViral PathogenesisImmunologyVirology	1993	2.2K
Phosphatidylinositol-3-OH kinase direct target of Ras Pablo Rodriguez‐Viciana, Patricia H. Warne, Ritu Dhand, Nature Signal TransductionSignaling PathwayReceptor Tyrosine KinaseCellular BiochemistryMedicine	1994	1.9K
An Adenovirus Mutant That Replicates Selectively in p53- Deficient Human Tumor Cells James R. Bischoff, David H. Kirn, Angelica Williams, Science Mutant AdenovirusAdenovirus MutantFunctional P53Mutant AdenovirusesMedicine	1996	1.8K
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer Fadlo R. Khuri, John Nemunaitis, Ian Ganly, Nature Medicine Intratumoral Onyx-015Neck CancerMedicinePathologyHead And Neck Cancer	2000	1.1K
Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant Robert L. Martuza, Amy Malick, James M. Markert, Science	1991	1K
Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses Ya‐Wen Yang, Qunyang Li, Hildegund C.J. Ertl, Journal of Virology Viral PathogenesisImmunologyRecombinant AdenovirusesAntigen ProcessingCd4 T Cell Responses	1995	1K
ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents Carla Heise, Adam Sampson-Johannes, Angelica Williams, Nature Medicine Tumor BiologyCancer-associated VirusOncogenic AgentMedicineTumor-specific Cytolysis	1997	944
Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis Ronald G. Crystal, Noel G. McElvaney, Melissa A. Rosenfeld, Nature Genetics Human Cftr CdnaRespiratory TractPathologyVirologyRespiratory Infection	1994	827
Stepwise dismantling of adenovirus 2 during entry into cells Urs F. Greber, Melanie Willetts, Paul Webster, Cell Viral ReplicationAdenovirus 2VirologyViral Structural ProteinMedicine	1993	811
An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Andrew J. Bett, Wael Haddara, L. Prevec, Proceedings of the National Academy of Sciences Viral ReplicationEngineeringSynthetic VirologyMolecular BiologyEarly Regions 1	1994	742

Page 1