Leptin: A pivotal mediator of intestinal inflammation in mice

Interleukin-10-deficient mice develop chronic enterocolitis

Ralf Kühn, Jürgen Löhler, D Rennick et al. · Cell · 1993 · 4.3K citations

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A Short-Term Study of Chimeric Monoclonal Antibody cA2 to Tumor Necrosis Factor α for Crohn's Disease

Stephan R. Targan, Stephen B. Hanauer, Sander J. H. van Deventer et al. · New England Journal of Medicine · 1997 · 3.2K citations · Full text

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A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

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Life Sciences, Immunology, Pathobiology +16

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

Graham M. Lord, Giuseppe Matarese, Jane K. Howard et al. · Nature · 1998 · 2.2K citations

Life Sciences, Endocrinology, Immunology +14

An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

Chrystelle Asseman, Smita Mauze, Michael W. Leach et al. · The Journal of Experimental Medicine · 1999 · 1.6K citations · Full text

Life Sciences, Immunology, Pathology +17