Concepedia

TGF-β upregulates CD70 expression and induces exhaustion of effector memory T cells in B-cell non-Hodgkin’s lymphoma

Z-Z Yang, D M Grote, B Xiu, Steve Ziesmer, Tammy Price-Troska, Lucy S. Hodge, David Yates, Anne J. Novak, Stephen M. Ansell

Leukemia · 2014 · 143 citations · 54 references

DOI

Concepts

References

54

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Cheryl L. Day, Daniel E. Kaufmann, Photini Kiepiela et al. · Nature · 2006 · 2.6K citations

, , +17

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

Kaori Sakuishi, Lionel Apétoh, Jenna M. Sullivan et al. · The Journal of Experimental Medicine · 2010 · 2.1K citations · Full text

, , +16

Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

Allan Zajac, Joseph N. Blattman, Kaja Murali‐Krishna et al. · The Journal of Experimental Medicine · 1998 · 2K citations · Full text

, , +17

Tumor antigen–specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired

Mojgan Ahmadzadeh, Laura A. Johnson, Bianca Heemskerk et al. · Blood · 2009 · 1.8K citations · Full text

, , +12

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

John H. Kehrl, Lalage M. Wakefield, Anita B. Roberts et al. · The Journal of Experimental Medicine · 1986 · 1.6K citations · Full text

, , +15