Concepedia

Publication | Open Access

Gene Inactivation of Proprotein Convertase Subtilisin/Kexin Type 9 Reduces Atherosclerosis in Mice

DOIFull Paper Access

227

Citations

40

References

2012

Year

Maxime Denis, Jadwiga Marcinkiewicz, Ahmed Zaid, Dany Gauthier, Steve Poirier, Claude Lazure, Nabil G. Seidah, Annik Prat
Circulation

Abstract

Altogether, our results show a direct relationship between PCSK9 and atherosclerosis. PCSK9 overexpression is proatherogenic, whereas its absence is protective.

References

YearCitations

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